The presence of mild ventriculomegaly should prompt a detailed ultrasound evaluation to define more precisely any structural anomalies and is sufficient reason to consider genetic testing.

Ultrasound A ... accurate prenatal test for Down syndrome, and is sometimes used to confirm amniocentesis or CVS results. The test usually occurs between 18 and 22 weeks of pregnancy.

Many investigators have reported the association between each isolated ultrasound marker and the risk for Down syndrome. Vintzileos and associates [19] reported the incidence of ultrasound markers ...