Hereby, we review the functions of microtubule cytoskeletal proteins in tumor cells and comprehensively examine the effects of microtubule-targeting agents on pancreatic carcinoma ... properties and ...

H1048 cells were cultured in DMEM:F12 (Gibco) supplemented with 10% FBS, 0.005 mg/ml insulin (Sigma), 0.01 mg/ml transferrin (Gibco), 30 nM sodium selenite (Sigma), 10 nM hydrocortisone (Sigma), 10 nM ...

A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...

Electron microscopy uses a beam of electrons to illuminate a sample and achieve much higher spatial resolution than light microscopy. Transmission electron microscopy generates an image of the ...

In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

As cancer cells adapt to therapies ... As reported in Biophotonics Discovery, the team developed a novel microscopy technique that uses a standard fluorescence microscope in combination with ...

Objective Pancreatic ductal adenocarcinoma (PDAC ... which hijacked low metastatic cancer cells for metastasis. The interleukin (IL)-33–ST2–TAMs axis was the primary driver for upregulating CXCL3 that ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...