Conventional human pluripotent stem cells at the primed pluripotent state are capable of generating all the embryonic lineages. However, their ...

Extraembryonic trophoblast lineages constitute the placenta, and are essential for individual development. In human early embryo development, these cells can be generated from totipotent blastomeres.

A guardian molecule ensures that liver cells do not lose their identity. This has been discovered by researchers from the German Cancer Research Center (DKFZ), the Hector Institute für Translational ...

Emerging findings suggest that viral DNA may play an important part in how embryos form, right after fertilization.

Researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.

Scientists in China have manipulated embryonic stem cells to create laboratory mice with two male parents that managed to ...

This study provides a valuable new resource to investigate the molecular basis of the particular features characterizing the pipefish embryo. The authors found both unique and shared gene expression ...

Chinese scientists have created the first mice with two fathers to reach adulthood. This was achieved by reprogramming ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

By using embryonic stem cell engineering, the researchers were able to reprogram the imprinted genes, effectively allowing ...

This team used a different approach, adding recombinase sites to transposons - mobile genetic elements - that randomly integrated in the genomes of human cell lines and mouse embryonic stem cells.

Our bodies are made of hundreds of different cells. Neurons, muscles, blood vessels, liver, kidney, etc., each are made of very different cell types. They differ in many respects: in biochemistry, ...