Ancient viral DNA embedded in the human genome has been linked to the genetic risks of certain neurodegenerative diseases, ...

As will become apparent in the following, we do not see the endogenous retroviruses ... immune sensors of foreign patterns. This in turn could lead to stimulation of an adaptive autoimmune response.

Autoantigen-reactive T and B cells can also be activated following recognition of viral antigens with similarity to self antigens (molecular mimicry ... of the type of immune response, the ...

The human genome contains remnants of ancient retroviruses, called human endogenous retroviruses ... to influence genetic activity and immune responses. Past studies have suggested that abnormal ...

Viral protein is made intracellularly and the protein is processed via the endogenous MHC class I pathway. DNA vaccines. DNA vaccines favor a cell-mediated immune response. DNA plasmid vector ...