Did you know that genes can mask and alter the effects of other genes? Could this process, called epistasis, be a key to understanding complex conditions like Alzheimer’s disease and diabetes?

Epistasis describes how gene interactions can affect phenotypes. Did you know that genes can mask each other's presence or combine to produce an entirely new trait? But what happens when two ...

In a new study, researchers have found that changes in two parts of the genome work together to influence alopecia risk.

Scientists have discovered an interaction between genes that increases the risk of developing a type of alopecia.

This paper addresses the important question of quantifying epistasis patterns, which affect the predictability of evolution, by reanalyzing a recently published combinatorial deep mutational scan ...

Alopecia refers to hair loss and can affect the scalp, eyebrows, eyelashes, and other areas of the body. There are different types of alopecia including an | Immunology ...

The challenges we face conducting genetic analyses are derived from the complexity of the genotype- and phenotype-mapping relationship that results from phenomena such as epistasis (gene–gene ...

Imagine your doctor calls you to discuss the results of your genetic testing. They tell you your results indicate you are ...

After submitting a query for a given gene, the user is returned a list of ... There are many challenges when it comes to detecting epistasis, and we propose that we will be able to utilize this ...