The Falke group is currently investigating the molecular mechanisms of on-off switching of components within the chemosensory array, especially the mechanisms by which transmembrane receptors bind ...

For example, prokaryotic organisms have sensors ... When a signaling molecule joins with an appropriate receptor on a cell surface, this binding triggers a chain of events that not only carries ...

Almost 35% of drugs approved by the Food and Drug Administration work by targeting G protein-coupled receptors (GPCRs), proteins embedded in cell membranes that allow cells to communicate with ...

For example, beta cells secrete insulin in ... through these receptors is disrupted in diabetes. Many classes of cell surface receptors exist, the largest of which is the GPCR family.

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...