News Medical on MSN14h
Study identifies vitamin E succinate as key to tumor growth control
High levels of fat mass and obesity-associated protein (FTO) have been linked to increased tumor growth and resistance to ...
technologynetworks17h
Vitamin E Succinate Helps Control Tumor Growth and Enhance Immunotherapy
Researchers at the University of Chicago Medicine identified vitamin E succinate (VES) as an effective agent in suppressing ...
BBC24d
Could a DNA diet test transform your health?
Variations in the FTO gene, also known as the ‘fat gene’, are strongly associated with a higher risk of obesity, particularly among certain ethnic groups. Research shows those who carry at ...
Frontiers8d
Comparison of the risk of obesity in the FTO rs9939609 genotype in a multiethnic group in Asia systematic review and meta-analysis
Based on previous research, there is a relationship between polymorphisms of the FTO gene and obesity not only in Asian ethnic group but also in Caucasian and Hispanic (5). They compared the risk of ...
gut.bmj10d
Targeting the oncogenic m6A demethylase FTO suppresses tumourigenesis and potentiates immune response in hepatocellular carcinoma
FTO inhibitor CS2 was used to examine the effects on anti-PD ... The details of the materials and methods used in this study including the cell culture techniques, gene manipulation in HCC cell lines, ...
Frontiers9d
Epigenetic Transgenerational Inheritance of the Effects of Obesogen Exposure
The authors analyzed F1-F6 generation sperm and concluded that the development of obesity was dependent on the binding of CTCF at two enhancer regions of the Fto gene and that eliminating the CTCF ...
eLife29d
3D genomic features across >50 diverse cell types reveal insights into the genomic architecture of childhood obesity
7 shows simple Gene Ontology (GO) biological process terms enrichment results ... in a temporal fashion at a given locus depending on cell state, including at the FTO locus 53. Our approach offers an ...