In this review, I summarize recent findings on the molecular mechanisms of Reelin activity. I also discuss possible strategies to enhance Reelin’s function. A complete understanding of Reelin function ...

DURING starvation, glycogenolysis is associated with the release of the enzymes phosphorylase and glycogen synthetase from insoluble granules into the cytoplasm. This event is accompanied by a ...

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

By contrast, solitary locusts at low density have limited ability in long-distance flight. However, the mechanisms underlying such flight capacity variation are poorly understood. Here, we found that ...

Microwave-fixation of the brain was employed to enable in situ snapshots of brain glycogen and metabolome as well as the phosphorylation-dependent activation state of GYS1. In conjunction with the ...

The stability of this protein complex appears to be related to phosphorylation mechanisms. Objective: To analyse lamin A/C phosphorylation in control and laminopathic muscle cells. Methods: Lamin A/C ...

Glycogen storage disease (GSD) refers to a group of rare genetic conditions that affect how the body stores and breaks down glycogen. The most common type is type I, also called von Gierke disease ...