Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating and fatal hereditary disorder that strikes in the prime of life, causing nerve cells in parts of the ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...

A new study of nerve cells affected by Huntington’s disease (HD) reveals that the disease-causing gene slowly expands over time but doesn't start causing harm until it hits a toxic threshold ...

Surprise Finding Sheds Light on What Causes Huntington's Disease, a Devastating Fatal Brain Disorder Scientists are unraveling the mystery of what triggers Huntington’s disease, a devastating ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

Nov. 13, 2024 — The Huntington's disease (HD) mutation eventually causes a fatal brain disease in adulthood, but a new study finds that early in life, children with the HD mutation have bigger ...