Hypertrophic cardiomyopathy (HCM) is an uncommon disease with significant consequences. Since the 1950s, major strides in understanding its etiology and pathogenesis have led to improved ...

Cardiac catheterization helps exclude coronary disease as the cause of angina in patients with risk factors for coronary atherosclerosis. [5] It can also be used to measure LV outflow tract ...

claiming a green light from the US regulator for mavacamten as a therapy for obstructive hypertrophic cardiomyopathy (HCM). Orally-active mavacamten – which was acquired by BMS when it bought ...

We herein will provide an overview of myocardial energy metabolism in the healthy heart, while describing the numerous perturbations that take place in various non-ischemic cardiomyopathies such as ...

Repeated cardiac sonography was consistent with stable non-progressive hypertrophic cardiomyopathy. At the age of 10 ... revealed a temporary improvement of the right ventricular pathology, but by 3 ...

Pathology Department, Royal Brompton and Harefield NHS ... left ventricular hypertrophy, hypertrophic cardiomyopathy, dilated cardiomyopathy, and arrhythmogenic right ventricular dysplasia; (2) ...

Hypertrophic cardiomyopathy is a common but underrecognized cardiac disorder characterized by a heterogenous phenotype that includes increased left ventricular thickness, outflow obstruction, ...

A genetic testing panel that assessed for 56 genes associated with hypertrophic cardiomyopathy, including the genes encoding myosin, titin, lamin, transthyretin, and the γ2 subunit of AMP ...

High-intensity exercise raises sudden cardiac death risk in young hypertrophic cardiomyopathy patients, independent of ...

The decrease in mortality, morbidity were seen with trametinib for children with RASopathy-associated hypertrophic cardiomyopathy. HealthDay News — For children with severe hypertrophic cardiomyopathy ...