The ratio of IgG4-plasma cells to IgG-positive plasma cells was about 50%. Collecting duct was compressed longitudinally by severe inflammation and fibrosis in renal cortex around cyst (Figure 2f).
The three studies demonstrated statistically significant reversal of liver fibrosis with leronlimab monotherapy (compared to an isotype IgG4 ... mechanism of action, binding to CCR5 receptors on ...
The three studies demonstrated statistically significant reversal of liver fibrosis with leronlimab monotherapy (compared to an isotype IgG4 control ... leronlimab’s core mechanism of action, binding ...
Our study, through the identification of plasma cells, fibroblasts, and Schwann cells, suggests potential parallels with other fibrotic diseases such as pulmonary fibrosis and keloids, indicating ...
Our data suggest that GAS5 regulates TCR-mediated activation and apoptosis in CD4 T cells during HIV infection through miR-21-mediated signaling. However, GAS5 effects on T cell exhaustion during HIV ...
Researchers have been trying for decades to stop the cells that damage the lung in people with pulmonary fibrosis. Now a team ...
Danés, principal investigator of the Cancer and Stem Cell Biology Lab at the Champalimaud Foundation, in Lisbon, has shown ...
hadassah.org.il Airway epithelial cells and immune cells participate in the inflammatory process responsible for much of the pathology found in the lung of patients with cystic fibrosis (CF). Intense ...
In this study, we have unravelled a novel mechanism of TAM-initiated fibrosis and the myofibroblast transition in facilitating PDAC metastasis. The interleukin (IL)-33–ST2–CXCL3–CXCR2 signalling ...
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