A team led by UT Southwestern Medical Center researchers has identified a key mechanism responsible for endosomal recycling ...
(right) Fusion with plasma membrane: mature viruses are captured ... HIV-1 is even able to re-use at its advantage the interaction between APCs and T cells to cross the intercellular space for ...
The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.
Researchers at UT Southwestern identified how SNX17 and Retriever interact to regulate endosomal recycling, a crucial process ...
DCs phagocytose antigens and whole microorganisms and place them into membrane-delimited compartments ... exclusive provider of such antigens; both intercellular protein channels and autophagy ...
The Affinity of Elongated Membrane-Tethered Ligands Determines Potency of T Cell Receptor Triggering
In the present study, we further investigated the interaction of ligand affinity and receptor dimensions in TCR triggering by creating artificial APCs (aAPCs) of 3T3 cells that express ...
While this is an incipient field, it has quickly been adopted in translational medicine for its potential to unravel cell-to-cell interactions and cellular ... highly activated T cells, IgG plasma ...
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