In patient-derived and animal tumour models, mubritinib suppressed glioblastoma stem cells and tumour growth by targeting ...

Neutrophil granulocytes, a type of immune cell, are indispensable for the defense against pathogens. However, if they migrate into injured tissue, for example into the brain after a stroke, they can ...

It is proposed that acidosis in the tumor microenvironment is an important stress factor and selection force for cancer cell somatic evolution. Acidic pH has pleiotropic effects on the proliferation, ...

and 5 mL of 1M HEPES and set to pH 7.5. 10 ... (Biolegend). Cells were then incubated with fluorescence-labelled antibodies (Supplementary Table 1) for surface staining in FACS buffer (PBS, 2% BSA) ...

I am happy to say that Samsung ended up doing the right thing and providing my credit. I am still wary of using their trade-in program again, but this particular case is resolved favorably ...

Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Physics and Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China ...

Objective Pancreatic ductal adenocarcinoma (PDAC ... which hijacked low metastatic cancer cells for metastasis. The interleukin (IL)-33–ST2–TAMs axis was the primary driver for upregulating CXCL3 that ...

Objective Innate immunity plays important roles in pancreatic ductal adenocarcinoma (PDAC), as non-T-cell-enriched tumour. Neutrophils are major players in innate immune system. Here, we aimed to ...