The distinct population of endothelial cells that line blood vessels in the insulin-producing "islets" of the human pancreas have been notoriously difficult to study, but Weill Cornell Medicine ...

Intercellular communication between tumor cells and cancer-associated fibroblasts (CAFs) plays a key role in tumorigenesis and progression, and CAFs generate an extracellular matrix that provides a ...

In future studies, the team will explore how CERS2's loss of function contributes to pancreatic beta cell dysfunction and assess CERS2 activity and sphingolipid metabolism as targets. Other ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

We take “islet beta cells aging” and “the pancreas senescence” as keywords ... The sample was repeated at least three times in the experiment. 2.3 Islet isolation and insulin secretion assay The ...

GRAIL is advancing blood-based cancer detection with Galleri. Find out why GRAL stock’s future hinges on successful trials and regulatory approval.

Researchers found that four weeks after cell transplantation, UP421 demonstrated the survival and function of pancreatic beta cells as measured circulating C-peptide, a biomarker indicating that ...

Notably, FIP excludes peri-pancreatic fat, also called extra-lobular fat (2, 3). The lack of clear differentiation between triglyceride accumulation in acinar cells, beta cells, or intra-pancreatic ...