Gene modification can encourage T cell growth, improving cancer treatment's success rate
Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...
Frontiers5d
Advances in the role of STAT3 in macrophage polarization
The physiological processes of cell growth, proliferation, differentiation, and apoptosis are closely related to STAT3, and it has been demonstrated that aberrant STAT3 expression has an impact on the ...
Frontiers5d
Regulation of the JAK2-STAT5 Pathway by Signaling Molecules in the Mammary Gland
Proper functioning of the JAK2-STAT5 signaling pathway relies on crosstalk ... Two isoforms of JAK (JAK1 and JAK2) are expressed in the mammary gland, and these factors are upstream of STAT. The ...
eLife4d
Drug combination prediction for cancer treatment using disease-specific drug response profiles and single-cell transcriptional signatures
retriever generates disease-specific transcriptional drug response signatures by merging transcriptional signatures over time, concentration, and cell-type. These signatures can then be matched to ...
gut.bmj4d
Single-cell omics in inflammatory bowel disease: recent insights and future clinical applications
Inflammatory bowel diseases (IBDs), which include ulcerative colitis (UC) and Crohn’s disease (CD), are chronic conditions ...