The cellular and molecular mechanisms that ensure the elaborate connection and function of the nervous system can then be dissected with single neuron resolution. How can one achieve this purpose?

Nader Yaghoubi, M.D., Ph.D., PathMaker’s Co-Founder and CEO, stated, “We are pleased to announce IRB approval for the CALM study, which allows us to commence enrollments shortly. Given the mechanisms ...

has developed a next-generation neuron labeling technology called NeuM. NeuM (Neuronal Membrane-selective) selectively labels neuronal membranes, visualizing neuronal structures and allowing real ...

The human brain is a complex powerhouse, responsible for orchestrating thoughts, emotions, and memories. Its nerve cells ...

After winning a breakthrough therapy designation for its Hunter syndrome enzyme replacement therapy, Denali Therapeutics is ...

Nonetheless, the time-consuming computation on neuron level and complex optimization limit their ... It pays more attention to some informative and representative data to overcome the labeling ...

Laboratory tests can monitor for renal toxicity and coagulation abnormalities, including acute severe low platelet counts, which have been observed after administration of some ASOs. Biogen licensed ...

For co-labeling studies, we scanned each laser line in an individual ... for use in RT-PCR cloning experiments to determine which RPTPγ variants are expressed in mixed neuron–astrocyte HC cultures, P0 ...

A second Phase 2 open-label 2 Biomarker trial in patients with more advanced ... the support cells of the central nervous system, and neuron loss in multiple brain regions. MSA affects at least 15,000 ...