Lewy body diseases (LBDs) are a class of debilitating neurodegenerative disorders linked to the abnormal aggregation of the ...

In mice, α-synuclein pathology spreads from the kidneys to the brain ... kidneys of 17 of 20 people with chronic kidney disease (CKD). Seven of them also had Lewy body- and Lewy neurite-like ...

Alpha-synuclein inhibitors are a class of investigational therapies targeting the pathological aggregation of alpha-synuclein, a protein implicated i ...

Lewy Body Dementia: What Is It Really ... This spotlight on such a little-known pathology has undoubtedly helped many people to better understand what it involved, both medically and personally.

Data from the first 16 weeks of the open-label extension phase of the RewinD-LB trial are expected in 1Q 2025 and will include data from ...

About Dementia with Lewy Bodies (DLB) DLB is the third most common ... in the hippocampus and associated Alzheimer’s Disease co-pathology – were excluded from the trial. The primary endpoint ...

New research uncovers how declining protein clearance mechanisms with age lead to Alzheimer’s, Parkinson’s, and other ...

Researchers have discovered how a cell surface protein called Aplp1 can play a role in spreading material responsible for Parkinson's disease from cell-to-cell in the brain.

pathology to impact ... Dementia With Lewy Bodies Has Been Difficult to Diagnose Early, but Comprehensive Cognitive Testing Could Change That Jan. 10, 2025 — Cognitive profiles for early ...