AF6 denotes afadin, GAP GTPase-activating protein, GEF guanine exchange factor, MEK mitogen-activated protein kinase kinase, MT mutant, Pi inorganic phosphate, P13K phosphoinositide 3-kinase ...

The endosomal pathway is essential for regulating cell signaling and cellular homeostasis. Rab5 positive early endosomes receive proteins from the plasma membrane. Dependent on a ubiquitin mark on the ...

MAPK cascades respond to various environmental stress factors by modulating associated gene expression, influencing plant hormone synthesis, and facilitating interactions with other environmental ...

Sepsis is defined as a life-threatening dysfunction due to a dysregulated host response to infection. It is a common and complex syndrome and is the leading cause of death in intensive care units. The ...

U.S. Army Air Forces commanders considered it one of the three premier American fighters, along with the P-51 Mustang and P-38 Lightning. The United States built more P-47s than any other fighter ...

as well as recent advances in the design of novel agents that are able to modulate the activity of these signalling cascades. mitogen activated protein kinase MAP kinase anti-inflammatory signal ...

School of Pharmacy, Key Laboratory of Molecular Pharmacology and Drug Evaluation (Yantai University), Ministry of Education, Collaborative Innovation Center of Advanced Drug Delivery System and ...