Nature10d
Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma
13 To define the enrichment of MYC pathway genes and the other correlated pathways or functional program at the individual sample level, we made a modification to the GSEA algorithm called ...
Medindia9mon
Deadliest Cancers may Respond to New Drug Treatment Strategy: Research
“We are excited by the work of Dr. Pourdehnad and colleagues and believe these results are an important advance in understanding the role of myc pathway dysregulation in multiple ...
News Medical15d
Targeting MYCN and MDM2 offers new hope for cancer therapy
The MYC family of proteins ... As a key survival signaling pathway, the MDM2/p53 axis is widely involved in the development of many tumors. Preclinical and clinical trials provide evidence ...