News Medical on MSN7d
How lymphoid tissues protect against viral infections
Researchers explore the cellular and molecular adaptations associated with human secondary lymphoid tissue in adults during ...
The Brighterside of News on MSN7d
Keto diet improves multiple sclerosis, IBD and arthritis symptoms
Diet plays a pivotal role in influencing autoimmune diseases like multiple sclerosis (MS), inflammatory bowel disease, and ...
Frontiers29d
IgG4-mediated M2 macrophage polarization in tertiary lymphoid structures of esophageal cancer: implications for immunosuppression
Finally, flow cytometry analysis is conducted using the BD C6 flow cytometer ... and the development ofGCs (n=3). Scale bar=60um. Macrophages in TLS and the adjacent mesenchymal tissue predominantly ...
gut.bmj11d
MerTK expressing hepatic macrophages promote the resolution of inflammation in acute liver failure
Design Flow cytometry, immunohistochemistry, confocal imaging and gene expression analyses determined the phenotype, functional/transcriptomic profile and tissue topography of MerTK+ ...
eLife3d
Identification of a sub-population of synovial mesenchymal stem cells with enhanced treatment efficacy in a rat model of Osteoarthritis
This important study focused on characterizing clonally derived MSC populations from the synovium of normal and osteoarthritis (OA) patients, demonstrating their potential to regenerate cartilage in ...
ahajournals.org15d
Abstract TP210: Myelin in the Macrophage Response to Intracerebral Hemorrhage-Relevant Signals
Murine bone marrow-derived macrophages were pretreated with myelin for 18 hours before stimulation with S100A9 or LPS. Cytokine concentrations of TNF, IL-6, CCL2, and IL-10 were measured by cytometric ...
News Medical on MSN2d
Gut microbes influence how well cancer patients respond to immunotherapy
Researchers discovered that gut microbiota-derived hexa-acylated LPS enhances the effectiveness of anti-PD-1 cancer ...
Frontiers9d
Crosstalk Between CD11b and Piezo1 Mediates Macrophage Responses to Mechanical Cues
Macrophages are versatile cells of the innate immune system ... RTK4530), used as an isotype control (both from BioLegend). Following repeated washes, flow cytometry was performed using BD LSRII (BD ...
gut.bmj11d
Adipose tissue macrophages induce hepatic neutrophil recruitment and macrophage accumulation in mice
Accumulation of CD11c + proinflammatory adipose tissue macrophages (ATM) is an important driver of ... CJM, MV and JvdG performed experiments. EW contributed to flow cytometry experimental design and ...
thorax.bmj5d
Inflammation in preschool cystic fibrosis is of mixed phenotype, extends beyond the lung and is differentially modified by CFTR modulators
Background Early-life inflammation has long been recognised as a key pathophysiological process in the evolution of cystic ...