The nucleation of microtubules is primarily facilitated by the gamma-tubulin ring complex (γ-TuRC), which serves as a template for microtubule assembly. Recent research has focused on ...
Mammalian cytoplasmic linker associated protein 1 and -2 (CLASP1 and -2) are microtubule (MT) plus-end tracking proteins that selectively stabilize MTs at the edge of cells and that promote MT ...
ULK1 complex initiates phagophore nucleation by phosphorylating components of the ... c-Jun N-terminal kinase 1; LC3, microtubule-associated protein 1A/1B-light chain 3; mTORC1, mammalian target of ...
Recently, a moonlighting function of Elongator has been identified in regulating the polarization of the microtubule cytoskeleton during asymmetric cell division. Elongator induces symmetry breaking ...
PAD12 tau can be used for both nucleation-dependent and multiple rounds of seeded assembly in vitro, as well as for the seeding of tau biosensor cells. PAD12 tau can be assembled into paired helical ...
autophagy induction signaling (A), membrane nucleation/AP formation (B), autophagy adaptor proteins (C) and AL formation/substrate degradation (e.g., lysosomal hydrolases or structural components)(D).
Zhejiang Key Laboratory of Excited-State Energy Conversion and Energy Storage, and Department of Chemistry, Zhejiang University, Hangzhou 310058, China ...
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