Efforts are focused on an enzyme known as p38 MAP kinase, which is a “master regulator” of production of IL-10. As well as blocking IL-10, inhibiting p38 MAP kinase also restores levels of ...

Kinases are enzymes that catalyze the addition of a phosphate group (PO43−) to substrates, usually proteins. The phosphate generally comes from adenosine triphosphate (ATP). Kinases and ...