News Medical on MSN8h
Study uncovers how MAGE-4 and Pten loss promote aggressive tumor growth
A study published in Science Advances reveals a novel strategy that allows tumors to evade the body's immune response critical for their elimination.
The EMBO Journal5d
Haploinsufficient phenotypes promote selection of PTEN and ARID1A-deficient clones in human colon
Monoallelic loss of PTEN and ARID1A is identified in normal colonic epithelium. The resulting haploinsufficient phenotypes ...
Targeted cancer cell therapy may slow endometrial cancer
"ERBB2 and PTEN are a part of different signaling pathways, but we believe they have a correlation in endometrial cancer," ...
Ignite Proteomics Announces Publication of Study Demonstrating Superiority of Protein Activation Analysis in Predicting Breast Cancer Therapy Response
The new study adds to growing evidence that measuring activated proteins is key to cancer therapy selection.Golden, CO, Feb. 10, 2025 (GLOBE ...
Ignite Proteomics announces publication of study on protein activation analysis
Ignite Proteomics announces the publication of a significant study in the British Journal of Cancer titled “Functional activation of the ...
pharmaphorum1y
AZ first to AKT finish line, but FDA clears narrow label
Mutations in PIK3CA, AKT1, and alterations in PTEN occur frequently ... of Truqap “reinforces the important role of the PI3K/AKT pathway in HR-positive breast cancer and the critical need ...
Nature20d
Deguelin's Role in Cancer Cell Proliferation and Apoptosis
The research indicated that deguelin's ability to enhance PTEN and KLF4 expression could ... forming new tumors. Signaling Pathways: Complex networks of molecules in a cell that work together ...