Notably, FIP excludes peri-pancreatic fat, also called extra-lobular fat (2, 3). The lack of clear differentiation between triglyceride accumulation in acinar cells, beta cells ... gray-scale imaging ...

An innovative organoid model mirrors the pancreas' complexity, generating all three key cell types to explore development and ...

Our perspective about glucose toxicity as it pertains to the pancreatic ß-cell is that the characteristic decreases in insulin synthesis and secretion are caused by decreased insulin gene expression.

In fact, previous studies have reported that granzyme B (GZMB)-expressing CD8+ T-cells have induce type 1 diabetes by killing pancreatic beta cells. Comparatively, GZMB-expressing KIR+ CD8+ T ...

Pancreas cells may produce a protein that can protect the brain from Alzheimer's disease. In individuals with Alzheimer's disease, a peptide known as amyloid-β accumulates and forms tangled plaques.

Patient-derived xenografts are considered the most reliable avatar of individual patient tumour. Pancreatic cancer cell lines are believed to poorly represent the tumour of origin. Establishment of ...

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14 Southern California Research Center for ALPD and Cirrhosis, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA The field of pancreatic stellate cell (PSC ...

Primary small cell carcinoma (SCC) of the pancreas is a rare disease with poor prognosis. Very few cases have been reported in the literature. It is a type of poorly differentiated variety of ...