Is your body resisting cancer treatment? Doctors list potential reasons for drug resistance
One of the most significant challenges in cancer treatment is the development of drug resistance by cancer cells, which often leads to treatment failure. When we say the body "resists" cancer ...
eLife2d
Scrutinized lipid utilization disrupts Amphotericin-B responsiveness in clinical isolates of Leishmania donovani
The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...
New Therapeutic Target Discovered for Lethal Form of Heart Failure
Researchers discovered that ALPK2, a heart-specific enzyme, may protect against HFpEF by activating TPM1 in heart muscle ...
Medindia4d
ALPK2: A Heart-Specific Enzyme Offers New Hope for Heart Failure
What is ALPK2, and how can it help treat heart failure? Researchers have found that this heart-specific enzyme may prevent ...
Too Old to Operate5d
Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax.
Disparate pathogenic mechanisms complicate precision-medicine efforts to treat diffuse large B-cell lymphoma (DLBCL), the most common lymphoma diagnosis. Though potentially curable with frontline ...