zju.edu.cn Objective Raf kinase inhibitor protein (RKIP) appears to control cancer cell metastasis and its expression in colonic tissue is related to colonic cancer development. We sought to identify ...
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Upstream reactivation of associated proteins such as Aurora Kinase A (AURKA), a serine/threonine kinase ... by stabilizing the interaction between newly formed KRASG12C protein and RAF, thus aiding ...
In addition, HER2 activation can activate Ras/Raf and MEK pathways, which favors cancer cells ... ADCC, antibody-dependent cellular cytotoxicity; Akt, protein kinase B; c-Cbl, Casitas B-lineage ...
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Alterations in the expression and activity of specific translation factors, and the uncoupling of translational regulation from inhibition by tumour cell stresses, such as hypoxia and nutrient ...