Cells are homogenized in guanidinium thiocyanate and the RNA is purified from the lysate by extraction with phenol-chloroform at reduced pH 1. This method allows many samples to be processed ...

RNA-based medicines are one of the most promising ways to fight human disease, as demonstrated by the recent successes of RNA ...

They discovered that these blobs, made from protein and RNA, were condensing on one side of the cell like raindrops in moist air, and dissolving again on the other side. In other words ...

Scientists have discovered that some tiny segments of RNA thought to be junk instead have a functional role in suppressing production of certain messenger RNAs and appear to help cells respond to ...

the researchers highlight a recent breakthrough development aimed at optimizing protoplast isolation methods and establishing standardized single-cell RNA sequencing (scRNA-seq) processes across ...

Technical variability can have a significant impact on single-cell experiments, affecting the accuracy and reproducibility of ...

"Our findings challenge previous assumptions about RNA transport," said the study's senior author Antony Jose, an associate professor of cell biology and molecular genetics at UMD. "We've learned ...

UMD researchers uncover key mechanisms in gene regulation that may lead to better design of RNA-based medicines.