Transposition is the process by which a DNA segment moves from a donor to a recipient DNA molecule. It occurs by cutting both strands of the donor and target DNA duplexes, followed by covalently ...

CREATE is a genome editing system that combines CRISPR/Cas9 with a modified LINE-1 retrotransposon machinery, enabling programmable and highly specific integration of large payload genes using only ...

This study provides important new insights into the contributions of local DNA features to the complex molecular mechanisms and dynamics of copy number variation (CNV) formation during adaptive ...