This is a pilot study highlighting a novel mechanism of tubular injury in cystinosis and requires further study in animal models to clarify its utility in clinical settings.

Tight junctions are a type of cell-cell junction found in epithelia that forms a barrier that is impermeable to the majority of soluble molecules between the two sides of the epithelium.

"These findings illuminate a critical mechanism that connects local synaptic activity to the broader gene expression changes necessary for learning and memory," said Mark Dell'Acqua, professor of ...

Terrified residents living next to a notorious junction dubbed 'Britain's worst' have named it 'Death Corner' and claimed that the police and local council won't change the speed limits on it ...