These skin findings, together with pulmonary lymphangioleiomyomatosis, pointed to the diagnosis of tuberous sclerosis complex (TSC). TSC is a genetic disorder characterized by the presence of ...

Approval was based on findings from the CodeBreaK 300 trial ... and neuroendocrine tumors as well as tuberous sclerosis complex. However, everolimus tablets for oral suspension, which are meant ...

People are more likely to have autism if they have related genetic disorders, such as fragile X syndrome, Rett syndrome, and tuberous sclerosis ... These findings and others form the basis ...

Background: Tuberous sclerosis complex (TSC) is a multisystem genetic disorder ... of considering this diagnosis even in the presence of less common cardiovascular findings. A comprehensive approach ...

The findings are helpful for understanding EGF/mTOR signal ... we report that endosomal-localized EGFR/Ezrin complex interacts with and triggers the inhibition of the Tuberous Sclerosis Complex (TSC ...

These findings show that c-Myc is essential for driving multipotent ... Accordingly, mice with constitutive mTORC1 activation in adipocytes induced by tuberous sclerosis complex (TSC1) deletion in ...

A team of researchers from the Sant Pau Research Institute (IR Sant Pau) has published a study in the Journal of ...

Background Tuberous sclerosis complex (TSC) is a genetic disease characterised by the growth of benign tumours. The Tuberous sclerosis Associated Neuropsychiatric Disorders (TAND) Checklist is used to ...

a Professor of Medicine and Multiple Sclerosis Clinical Research Chair at Dalhousie University. While people with MS consistently showed elevated risk, the findings suggest a broader need for ...

Low doses of glucocorticoids added to immunosuppression yield no significant benefit for skin fibrosis in early diffuse ...

Mice with tuberous sclerosis complex 1 (TSC1) or Rheb deletion specifically in the myeloid lineage were generated and subjected to intra-articular injection of collagenase (collagenase-induced ...

FRIDAY, Jan. 24, 2025 (HealthDay News) -- The menopausal transition may represent an inflection point for worsening of multiple sclerosis ... Significant findings persisted when adjusting for ...