Greatwall, a conserved MAST-like kinase with crucial mitotic entry functions, is curiously absent in worms. Here, the single ...

Treating older people with diabetes is challenging due to multiple medical comorbidities that might interfere with patients' ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Yeah, so the EGFR mutation lung cancer field has really expanded. We usually think about EGFR as the classical mutation, deletion 19 and 858R mutation. But in the last, I will say, five to 10 ...

Conclusion Our results show that myeloid cells support immune evasion in pancreatic cancer through EGFR/MAPK-dependent regulation of PD-L1 expression on tumour cells. Derailing this crosstalk between ...

1Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang, China. 2Benxi Institute of Pharmaceutical Research, Shenyang Pharmaceutical University, Benxi, China. Search for other works ...

Department of Biology, University of Naples Federico II, Naples, Italy Telethon Institute of Genetics and Medicine, Naples, Italy U.O.C. Genetica Medica, IRCCS Istituto Giannina Gaslini, Genova, Italy ...

Overall, digital pathways in education and skills development can be seen as the interplay of two dimensions: (1) depth of digital transitions, the extent to which public policy efforts take a ...

Department of Neurosurgery, Jiangxi Provincial People’s Hospital, The First Affiliated Hospital of Nanchang Medical College, No. 152 Aiguo Road, Nanchang, Jiangxi 330006, China Department of ...

Basically, ERAS targets RAS/MAPK pathways, which helps prevent cancerous ... The first one is for KRAS-mutated solid tumors, and the latter is for EGFR and RAS/MAPK solid tumors.

The role of stereotactic radiotherapy in brain metastases from gastrointestinal cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Gastrointestinal Cancers Symposium. This abstract does not ...