One person is dead and two others were injured following what investigators believe was a wrong-way crash involving three ...

California Highway Patrol officers responded at 4:06 a.m. to the southbound 405 near the Valley Vista Boulevard exit.

At least one person was killed in a reported wrong-way crash on the 405 Freeway in Encino that temporarily shut down of all southbound lanes Tuesday morning.

Three lanes of the southbound 405 Freeway in Encino have reopened after a deadly crash left one person dead Tuesday morning.

The California Highway Patrol officers responded at 4:06 a.m. Tuesday to the southbound San Diego (405) Freeway near the ...

At least one person was killed and two others were injured following a deadly crash on the southbound lanes of the 405 Freeway.

An SUV was reportedly driving 60 to 70 mph northbound in the southbound carpool lanes of the 405 Freeway near Getty Center Drive just after 4 a.m. Tuesday, according to California Highway Patrol logs.

A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks shut down traffic on all lanes early Tuesday.

A deadly wrong-way crash on the southbound 405 Freeway in Sherman Oaks shut down traffic on all lanes early Tuesday.

One person was killed and at least two others are in critical condition following a multi-vehicle collision involving a wrong-way driver that backed up traffic Tuesday for miles on the San Diego (405) ...