A new, streamlined AAV purification process that is both universal and scalable could ease commercialization constraint.

Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

Nirsevimab is protective against RSV infections and coinfections, which suggests there is no replacement of RSV with other viruses post-nirsevimab administration.

Biotium, a leading provider of innovative fluorescent reagents and kits for life science research, proudly announces the release of EMBER™ Ultra Gel Kits for RNA and DNA gel electrophoresis.

Biotium, a leading provider of innovative fluorescent reagents and kits for life science research, proudly announces the release of EMBER™ Ultra Gel Kits for RNA and DNA gel electrophoresis.

Financial writer recommends Voyager Therapeutics, Inc. for high-risk investors due to promising preclinical Alzheimer's ...

More information: Meirui An et al, In vivo base editing extends lifespan of a humanized mouse model of prion disease, Nature Medicine (2025). DOI: 10.1038/s41591-024-03466-w . www.nature.com ...

Researchers have developed a gene-editing treatment for prion disease that extends lifespan by about 50 percent in a mouse model of ... a pair of adeno-associated viruses (AAVs) to package and ...

Building on previous work by the vector-engineering lab of Ben Deverman at the Broad, the team developed a pair of adeno-associated viruses (AAVs) to package and deliver the base-editing machinery ...

As for delivery systems, the family of adeno-associated virus (AAV) vectors already provides ... This strategy, if successful, could be a model for the approximately 7,000 genetic diseases where ...

Lactylation is a reversible, covalent, post-translational modification of proteins. It happens exclusively on lysine residues, where it influences protein structure, stability, localization, and ...