Recognition of specific antigen through the B-cell receptor (BCR) stimulates the activation ... of encountering cognate antigen 3. The T-cell zone, or paracortex, which is adjacent to the ...

Only this time the antigen is whole and B cells don't keep it to themselves ... variety of lectins and scavenger receptors that facilitate direct or indirect recognition of carbohydrate patterns ...

and granzyme B but which did not express TRBC1 chain (a marker for expression of a T-cell antigen receptor constant beta chain; uniform positivity or negativity indicates clonality) or CD8.

Some recent studies have suggested that T cells can become activated via recognition ... unknown. B cells contribute to the rejection of skin allografts by presenting donor antigens to T cells ...

Researchers found that bioengineered CAR-T cells when mixed with other immune cells can "donate" proteins, suggesting ...

Engineered immune cells called CAR-T cells are used in the treatment of cancer. Researchers from Uppsala University have now ...

Chimeric antigen receptor-T (CAR-T) cell therapy, initially successful in hematologic malignancies, presents a promising avenue for treating solid tumors, including CRC. This review explores the ...

In a breakthrough for influenza research, scientists have discovered immune cells that can recognize influenza (flu) viruses ...

Transplanted organs express donor MHC molecules, resulting in 2 pathways of antigen recognition (allorecognition ... antigen and is delivered via the T-cell receptor. The second signal ...

View Full Profile. Learn about our Editorial Policies. Chimeric antigen receptor (CAR) T cell therapy leverages patients’ immune systems to fight cancer. This immunotherapy greatly expanded treatment ...