Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...

The ECMatrix from Millipore, which is used in the company's cell migration kits, is also a reconstituted basement membrane matrix of proteins derived from EHS mouse tumor cells. Another important ...

The method developed by IBEC's Biomimetic Systems for Cell Engineering group is based on the imprinting of defined patterns of key proteins, such as Wnt3a and EphrinB1, onto a basement membrane.

Collective cell migration is defined as the coordinated ... Simple 2D monolayers of cells move either constitutively across an intact basement membrane, such as the gut intestinal epithelium ...

D tumoroid models transform cancer research, accurately reflecting tumor biology and enabling effective drug testing and ...

The paradigm of stellate cell activation provides an important ... is to store vitamin A and probably to maintain the normal basement membrane-type matrix. However, numerous in vivo and in vitro ...

Explore the role of the extracellular matrix (ECM) in prostate cancer progression and discover natural therapies, including milk thistle, turmeric, and green tea, that target the tumor ...

The fatty membrane surrounding every living cell is a vibrant environment where countless biological processes take place.

Laboratory for Research on the Structure of Matter (LRSM), University of Pennsylvania, Philadelphia, United States ...

Scientists have revealed the secret to the structural integrity of tiny particles that transport cargo from cell to cell through ... special proteins that keep their membranes intact as they ...

Current optical and electron microscopy imaging techniques are not suited for measuring the dynamic characteristics of living microorganisms at tiny scales due to complex sample preparation methods or ...

Biologists had long believed that bringing order and organization to the chaos of molecules inside a cell depended on membrane-bound compartments called organelles, such as the mitochondria.