Hydroxyzine and Benadryl are both sedating antihistamines. They share many similarities but have different approved uses, ...

Benadryl (diphenhydramine) is the brand name for an OTC antihistamine often used to relieve allergy symptoms and itchy skin from bug bites or hives. Benadryl’s sedating properties may help ...

When treating mild allergic reactions, allergists and pediatricians prefer children’s Zyrtec over children’s Benadryl. OTC allergy medications cannot treat extreme allergic reactions ...

These include sleep aids and allergy drugs that contain antihistamines, such as: diphenhydramine (Benadryl) doxylamine succinate (Nyquil) While diphenhydramine and doxylamine succinate are ...

The Food and Drug Administration (FDA) has not approved Benadryl, which contains the active ingredient diphenhydramine, to treat anxiety. The medication is also not intended for long-term use.