Prolonged exposure to microgravity in space weakens the heart muscle and disrupts the heart’s rhythm, Johns Hopkins ...

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Robert Blaustein, M.D., Ph.D., joins the Company as Chief Development Officer, responsible for leading EDG-7500, a novel cardiac sarcomere modulator in Phase 2 development, as well as the ...

Kevin Koch, the President and CEO of Edgewise Therapeutics , Inc. (NASDAQ:EWTX), a biotechnology company with a market capitalization of $2.5 billion, recently executed a series of stock transactions, ...

TTN (titin) is the third myofilament type of the cardiac sarcomere and performs important functions that include generating passive tension. Changes in TTN expression are associated with cardiac ...

Maturation and functionality of cardiac cell types were determined by several criteria, including contractile force and relaxations measured by analyzing pole deflection, well-defined sarcomere ...

Echocardiograms were acquired to assess cardiac contraction in the affected myocardial segment ... with significant associations with the sarcomere, Z-disc, and actin binding. Conclusion: IPC induces ...