Chromatin fiber's genomic 'memory' governs the building blocks of life, study reveals
Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering ...
eLife20h
Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Megakaryocytes form a three-dimensional (3D) cage composed of laminin and collagen IV connected to the basement membrane surrounding them. This microarchitecture stabilizes megakaryocytes within their ...
Sickle Cell Disease Is A Genetic Disorder That Causes Lifelong Suffering Here's What You Need To Know
Right now, approximately 20 billion red blood cells are busy travelling through your blood vessels. They are delivering oxygen to all the different t ...
The EMBO Journal4h
Pharmacological CDK4/6 inhibition promotes vulnerability to lysosomotropic agents in breast cancer
Cell cycle re-entry of senescent breast cancer cells after CDK4/6 inhibition (CDK4/6i) constitutes a major source of disease ...
eLife5h
Strikingly different neurotransmitter release strategies in dopaminergic subclasses
This study presents solid evidence for distinct neurotransmitter release modalities between two subclasses of dopaminergic neurons in the olfactory bulb, highlighting an important finding that ...
IEEE Spectrum on MSN7h
AI Reveals Hidden Interior Design Rules of the Cell
The model has uncovered a hidden layer of molecular code that shapes biological organization, adding new dimensions of ...