Researchers are enhancing the best features of AAV capsids and overcoming their limitations to accelerate gene-based therapies.

Thus, enzymes modified to contain protein transduction motifs may represent ... nuclear or cytoplasmic reporter/fusion proteins into cells. Our work extends the application of this motif to ...

The findings highlight the significance of frequency-selective cellular responses in developmental biology, providing valuable insights into the intercellular signal transduction mechanisms.

Ad5 vectors transduce a wide range of cell types. They utilize the Coxsackie-Adenovirus Receptor (CAR) to enter cells. Transduction efficiency is related to the level of CAR expression on the cell ...

Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

A research team led by Dr. Tetsuya Muramoto from the Faculty of Science at Toho University has demonstrated the mechanisms by which periodic chemical signal frequencies in cells regulate gene ...

Researchers have identified a method to enhance the effectiveness of a promising cancer treatment. They found that modifying ...

Researchers identify target to enhance NK cell function for liver cancer therapy in Korea New insights into immune cell dynamics could lead to innovative therapies for cancer in Korea.

If there is one thing that is known about the mechanisms that govern signal transduction, it's that not very much is known. When signaling molecules bind to a cellular receptor, they set off a chain ...