This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

MicroRNAs (miRNAs) and the gut microbiome are key regulators of human health, with emerging evidence highlighting their complex, bidirectional interactions in chronic diseases. miRNAs, influence gene ...

RARRES1-correlated genes were obtained from the UALCAN database and subjected to Gene Ontology (GO) enrichment and protein–protein interaction (PPI) network analyses. The correlation analysis between ...

Misregulation of protein–protein interactions (PPIs) underlies many diseases ... crowded environment. This makes it complementary and bridges the dilute biochemical assays and complex cellular studies ...

They then convert the guide RNAs to complementary DNA, creating "barcodes" of the gene knocked out in each ... one day even enable studies of the interactions between multiple genes.

Department of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania 19104, United States Department of Materials Science and Engineering, University of Delaware, Newark, Delaware 19716, ...

The team further verified that disruptions in the direct interaction between IPMK and SRF lead to the reduced functionality and activity of SRF, causing severe impairments in gene expression.

“The biggest aha-moment for me has been that being stressed for even 5 to 10 minutes can reshape my biology at the level of gene expression ... of stress and its interaction with the brain ...

Antonio Pichillá Quiacaín working in his studio, San Pedro La Laguna, Guatemala. Courtesy of the Artist. Over 130 galleries are exhibiting at the 37 th edition of London Art Fair, which retains ...