[8] Hypospadias is also seen in Wolf-Hirschhorn syndrome, a rare chromosomal disorder with multiple dysmorphic features and midline defects, and with Denys-Drash syndrome (Wilms' tumor).

In addition, WT1 is expressed in the kidney and gonad, hence the association of Wilms’ tumour and gonadal dysgenesis in Denys-Drash syndrome, for example. The undifferentiated gonad is capable of ...

METHODS A retrospective study of a register of cases of male undermasculinisation (20 with abnormal testes, eight with 5α-reductase deficiency, three with testosterone biosynthetic defects, seven with ...

Asperger's syndrome refers to a high-functioning form of autism. Although it was once classified as its own condition, Asperger’s is no longer an official diagnosis in the Diagnostic and ...

The most common diagnoses were congenital adrenal hyperplasia (14%), androgen insensitivity syndrome (10%), mixed gonadal dysgenesis (8%), clitoral/labial anomalies (7%), hypogonadotropic ...

Mutations in the NeuroD/BETA2 gene have been shown to associate with type 2 diabetes. In the present study, we examined mutations in the NeuroD/BETA2 gene for association with either type 1 or 2 ...

gd in Dec. Drash On Ruby 18-1 (11-3) In rear, pushed along and headway before 3 out where mistake and blundered, soon pushed along to take 4th before 2 out, plugged on, no impression, 3rd of 11 ...

Metabolic syndrome is a constellation of conditions that together increase the risk of type 2 diabetes, stroke, and cardiovascular problems, including heart attack. The features of metabolic syndrome ...

Maria Iandolo New, who passed away on July 26, 2024, at the age of 95, was the child of Italian immigrants who came to America as professional musicians. She grew up in the Little Italy section of ...

What is Zollinger-Ellison syndrome? Zollinger-Ellison syndrome (ZES) is a rare digestive disorder. If you have ZES, you likely have 1 or more tumors in the first part of the small intestine, the ...

Objective: A firm diagnosis revealing the etiology of disorders/differences of sex development (DSD) is most helpful in guiding clinical management. The aim of this study is to investigate molecular ...