'I had my healthy stomach removed in my 20s after my aunt died'
A man whose aunt died of cancer, and whose mum then found out she had the illness, had his healthy stomach removed after ...
Davis Enterprise7d
UCD: Outside-in signaling shows route into cancer cells
A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals ...
Blood vessel growth factor alleviates anxious behaviors in mouse study
Anxiety disorders, characterized by an excessive apprehension about real or perceived threats and dysfunctional behaviors aimed at avoiding these threats, are among the most common mental health ...
Frontiers28d
GRHL2-HER3 and E-cadherin mediate EGFR-bypass drug resistance in lung cancer cells
Additionally, ER cells showed increased cell-cell adhesion, linked to upregulated E-cadherin. E-cadherin was found to be vital for erlotinib resistance, largely independent of GRHL2, highlighting ...
C&EN1mon
Delivery of N-Cadherin Targeting Peptides to Vascular Tissues by Surface-Modified Polyurethane Nanoparticles via a Drug-Coated Balloon
Translational Biology and Engineering Program, Ted Rogers Centre for Heart Research, Toronto, Ontario M5G 1M1, Canada ...
gut.bmj2mon
Chronicles of a cancer foretold: 35 years of gastric cancer risk assessment
More than 15 years ago, linkage analysis implicated germline mutations in the CDH1 tumour-suppressor gene (encoding the protein E-cadherin) as primary involved in the onset of hereditary signet-ring ...