The Medical University of South Carolina Health has established the Rena N. Grant Sickle Cell Center to help treat those ...

The high cost of sickle cell gene therapies is pushing private insurers and Medicaid programs to develop new payment models.

Here we report that activation of poly(ADP-ribose) polymerase (PARP) is an important factor in the pathogenesis of endothelial dysfunction ... eNOS activity and cell function in endothelial ...

A cutting-edge gene therapy has been approved for NHS use for some patients with severe sickle cell disease. Casgevy, also known as exa-cel, was the first treatment to be licensed using gene ...

To determine whether the endothelium is activated in this disease, we studied the number, origin, and surface phenotype of circulating endothelial cells in patients with sickle cell anemia.

This article is part of a Health Affairs Forefront series on “The Future of Sickle Cell Disease Research and ... to other blood cells and to vascular endothelial cells. These cellular ...

Sickle cell anaemia, a hereditary condition that primarily affects African and Mediterranean populations, continues to pose significant health challenges. In Uganda, where the disease is prevalent ...

Novo Nordisk is opening a new front in its fight against sickle cell disease, inking a deal with IMMvention Therapeutix to co-develop oral treatments for the red blood cell disorder and other ...

Instead of using rays, chemotherapy uses drugs to do battle with the disease. It's the most common treatment for small cell lung cancer and often takes several months to complete. The treatment ...

Hearing so much focus on executive dysfunction in recent years has been enlightening. I haven't always known the term, but executive dysfunction has been my thing since my inception. In the first ...