Northwestern Medicine scientists have discovered new details about how the human genome produces instructions for creating proteins and cells, the building blocks of life, according to a pioneering ...
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...
Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs). Here, using a ...
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