β-arrestin and kinase suppressor of RAS (KSR) 23. In addition to ERK, two other MAPK pathways are crucial in immune cells: the JUN N-terminal kinase (JNK; also known as MAPK8) pathway and the p38 ...
Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...
Spatiotemporal network dynamics govern cell fate decisions. We use the extracellular signal-regulated kinase (ERK) pathway as a paradigm to describe how temporal activation kinetics and spatial ...
Drug major Pfizer Inc. (PFE) announced Monday positive topline results from the progression-free survival or PFS analysis of the ...