This important study demonstrates the potential of synthetic gene circuits to detect and target aberrant RAS activity in cancer cell lines. The circuit design is novel and the evidence supporting the ...

Aberrant activation of the Ras/Raf/MAPK/ERK kinase/extracellular signal-regulated kinase cascade and the VEGF pathway are commonly observed in breast cancer cells leading to malignant cell ...

inspired by the promise of targeting cancer-associated molecular pathways upstream of other targets like RAS/ERK MAPK, which drive cellular proliferation and survival. According to BridgeBio and ...

and commercializing therapies for patients with RAS/MAPK pathway-driven cancers, today announced its participation in the Guggenheim Securities SMID Cap Biotech Conference being held at the Lotte ...

However, mechanistic studies to support the conclusion that mitochondrial function is increased in the tumours remain incomplete and would benefit from experiments that would directly interrogate ...

Dysregulated proteins, differentially phosphorylated kinases and proteins involved in Rho-GTPase pathway is highlighted in the schematic diagram. Our findings imply that differential MAPK and AKT ...

After hours: February 7 at 6:46:14 PM EST Loading Chart for VSTM ...

Upcoming events RAeS Flight Operations Conference 2025: Single Pilot Operations - Logical Progression or a Step Too Far? The RAeS Flight Operations Conference 2025 will gather industry leaders from ...