Adrenomedullin disrupts insulin signaling in blood vessels, leading to systemic insulin resistance in obesity-associated type 2 diabetes.

In summary, enalapril significantly mitigated multiple pathological markers associated with aging, including lipid droplets, amyloid, glycogen deposition, and fibrosis, in the brain, kidneys, liver, ...

Peptides have emerged as a fascinating class of biomolecules with multifaceted roles across biological systems. Vesugen, a ...

Rice lab pioneers an assembly kit for synthetic sense-and-respond circuits in human cells. Rice University bioengineers have ...

Dr. Marwan G. Fakih explains that KRAS mutations, found in 45% of patients with colorectal cancer, include the rare KRAS G12C mutation, leading to Lumakras approval.

Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Another significant area of research has been the role of heterotrimeric G proteins in mediating plant responses to abiotic stress. These proteins are involved in various signaling pathways that ...

A thorough examination of modern drugs that target particular receptors and metabolic pathways for glucose and fat metabolism is presented. Recent research has revealed innovative targets and ...

In this section, signal-transduction proteins and pathways that convert the chemical stimulus to a cell into a positive or negative regenerative cellular response are listed.