Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

New genetic research shows why some people develop deadly Huntington's disease earlier than others. The findings could lead to better treatments.

“A lot was known about Huntington’s disease before we started this work ... more rapidly in some neurons than others and how the CAG repeats over 150 repeats trigger cell death.

Huntington's disease kills a population of cells called ... Seeking to understand the direct biological effects of CAG-repeat length, the researchers adapted single-cell RNA-sequencing to help ...

Lead author, Professor Sarah Tabrizi (UCL Huntington’s Disease Research Centre and UK Dementia Research Institute at UCL), said: “Our study underpins the importance of somatic CAG repeat expansion ...

The findings, which could lead to new ways to prevent or treat the disease, have been reported in Cell. The mutations that cause Huntington's involve a repeat of a three base pair sequence: CAG in the ...

Huntington's disease kills a population of cells called ... Seeking to understand the direct biological effects of CAG-repeat length, the researchers adapted single-cell RNA-sequencing to help ...

Lead author, Professor Sarah Tabrizi (UCL Huntington's Disease Research Centre and UK Dementia Research Institute at UCL), said: "Our study underpins the importance of somatic CAG repeat expansion ...

Huntington’s disease kills a population of cells called ... Seeking to understand the direct biological effects of CAG-repeat length, the researchers adapted single-cell RNA-sequencing to ...

Huntington's disease kills a population of cells called ... Seeking to understand the direct biological effects of CAG-repeat length, the researchers adapted single-cell RNA-sequencing to help ...