Symptoms of Huntington's disease appear late in life. Research reveals how DNA repeats grow toxic over time, explaining the ...

This study presents a valuable finding on the alterations in the autophagic-lysosomal pathway in a Huntington's disease model. The evidence supporting the claims of the authors is solid. However, the ...

The HDBuzz team caught up with editor emeritus and Huntington's disease specialist, Prof Ed Wild to hear his thoughts on what ...

Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

People genetically susceptible to Huntington's disease often see their movement ... This happens repeatedly until the CAG/CTG repeats expand enough to interfere with the function of the huntingtin ...

People genetically susceptible to Huntington’s disease often see their movement ... This happens repeatedly until the CAG/CTG repeats expand enough to interfere with the function of the ...

They focused on the Huntington's mutation, which involves a stretch of DNA in a particular gene where a three-letter sequence -- CAG ... DNA repeats may be a better way to target the disease ...

The findings, which could lead to new ways to prevent or treat the disease, have been reported in Cell. The mutations that cause Huntington's involve a repeat of a three base pair sequence: CAG in the ...

People who develop Huntington’s disease have an expansion of these CAG repeats, like a genetic stutter. However, some cells are more vulnerable than others to these effects of HD. Even though the CAG ...

They focused on the Huntington's mutation, which involves a stretch of DNA in a particular gene where a three-letter sequence—CAG ... DNA repeats may be a better way to target the disease ...

For many people, the symptoms of Huntington's disease will not begin to show ... a cell might slowly repeat CAG triplets at first, gaining a few extra copies over decades until it gains momentum ...