In a pair of studies of Huntington’s disease published this week ... Even decades before symptoms are predicted to arise, MRI scans of people with the Htt risk gene show reductions in striatal ...

Jan. 28, 2025 /PRNewswire/ -- Huntington Medical Research Institutes ... heart's function and help reduce risk for cardiovascular disease among e-cigarette users." This pioneering approach ...

Other kinds of tests used to diagnose neurologic disease include genetic testing (for genetic causes of diseases such as Huntington’s disease) and screening of blood or other fluids for ...

Roche announces positive results from EMBARK phase III study of Elevidys in ambulatory individuals with DMD: Basel Tuesday, January 28, 2025, 11:00 Hrs [IST] Roche announced posit ...

Roche has reported positive results from the second year of the EMBARK Phase III trial of Elevidys (delandistrogene moxeparvovec), the first approv ...

Huntington’s disease symptoms are linked to expanding DNA repeats (CAG) that become toxic in brain cells over time The "ticking DNA clock" accelerates after 80 repeats, killing neurons within ...

For many people, the symptoms of Huntington's disease will not begin to show for decades. The genetic disorder is incurable but it is not uncommon for sufferers to reach middle-age before the ...

Subtle signs of neurodegeneration can be detected in blood, CSF, and neuroimaging, up to 20 years before the motor symptoms ...

This type of "somatic expansion" occurs in only the specific types of brain cells that later die in Huntington's disease. Only once a cell's DNA expansion reaches a threshold number of CAGs ...

CAMBRIDGE, Massachusetts ‒ For decades it's been one of the defining mysteries of Huntington's disease. Why does the terrible devastation of mind and body start earlier in some people who ...

The field of Huntington’s disease research has been undergoing a radical reshaping of how the brain-ravaging disease — and what drives it — is understood. After decades focused on the notion ...